John Libbey Eurotext

European Journal of Dermatology


Rituximab revisited: successful management of severe childhood atopic dermatitis Volume 29, numéro 1, January-February 2019


  • Figure 1
1 Department of Dermatology, Hospital de Santo António dos Capuchos,
2 Department of Paediatrics, Hospital de Dona Estefânia, Centro Hospitalar de Lisboa Central, Lisbon, Portugal

Atopic dermatitis (AD) is a chronic inflammatory disease affecting up to 25% of the paediatric population. A subset of patients follows a recalcitrant course for which there is an unmet need for effective therapy. In rarer instances, an underlying primary immunodeficiency, such as hyper-IgE syndrome (HIES), should be suspected.A seven-year-old Caucasian boy from non-consanguineous parents presented with widespread, intensely pruritic ill-defined erythematous plaques (figure 1A-C). Severe atopic eczema [...]