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European Journal of Dermatology

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Rapid growth of congenital angioma in an HIV patient with POEMS syndrome Volume 30, numéro 1, January-February 2020

Illustrations


  • Figure 1
Auteurs
1 Department of Dermatology, University Hospital Zurich, Zurich, Switzerland
2 Faculty of Medicine, University of Zurich, Zurich, Switzerland
3 Hautärzte-Zentrum am Zuerisee, Zurich, Switzerland
4 Department of Hematology, University Hospital Zurich, Zurich, Switzerland
5 Department of Dermatology and Allergology, LMU Munich, Munich, Germany
6 Medical Campus Davos, Davos, Switzerland

Polyradiculoneuropathy, organomegaly, endocrinopathy, monoclonal plasma cell disorder and skin changes are the main features of the rare paraneoplastic POEMS syndrome [1] (supplementary table 1). Of patients with POEMS, 24-44% develop angiomas, which histologically exhibit tufted or glomeruloid features. These variants are thought to correspond to different stages of endothelial proliferation. The mechanisms underlying this remain largely unknown. Vascular endothelial growth factor (VEGF) may be [...]