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European Journal of Dermatology

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Radiotherapy-induced or focally enhanced autoimmune blistering diseases Volume 29, numéro 6, November-December 2019

Illustrations


  • Figure 1
Auteurs
1 Service de Dermatologie, Centre Hospitalier Lyon Sud, Hospices Civils de Lyon, Lyon,
2 Service d’Anatomopathologie, Centre Hospitalier Lyon Sud, Hospices Civils de Lyon, Lyon,
3 Laboratoire d’Immunopathologie, Centre Hospitalier Universitaire de Rouen, Rouen,
4 Service de Radiothérapie-oncologie, Centre Hospitalier Lyon Sud, Hospices Civils de Lyon, Lyon,
5 Direction de la Recherche Clinique et de l’innovation, Hospices Civils de Lyon, Lyon,
6 UFR de Médecine Lyon-Sud Charles Mérieux, Université Claude Bernard Lyon 1, Lyon, France

Onset or exacerbation of cutaneous blistering diseases following radiotherapy is rarely reported. We report our experience by describing three clinical cases.Patient 1: an 85-year-old woman treated by radiation therapy for Merkel cell carcinoma affecting the left elbow (figure 1A) developed blisters limited to the irradiated area of the left arm six months later (figure 1B). Histopathology revealed a subepidermal blister with an inflammatory infiltrate composed of eosinophils. Direct immunofluorescence [...]