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European Journal of Dermatology

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Is gliclazide a new antidiabetic drug implicated in the pathogenesis of ocular mucous membrane pemphigoid? Volume 28, numéro 3, May-June 2018

Illustrations


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Auteurs
1 University of Genoa, Dissal, Department of Dermatology, San Martino Policlinic Hospital, Genoa, Italy
2 Molecular and Cell Biology Laboratory, Istituto Dermopatico dell’Immacolata (IDI)-IRCCS FLMM, Rome, Italy
3 U.C. Oculistica, Ospedale Padre Antero Micone-ASL3 Genovese, Genoa, Italy
4 Ospedale Villa Scassi, Genoa, Italy

Induced mucous membrane pemphigoid (MMP) is an autoimmune blistering disorder characterized by subepithelial bullae with predominant involvement of mucous membranes. It is clinically, immunologically and histopathologically indistinguishable from idiopathic MMP. In most cases, induced MMP is due to topical agents, whereas systemic drugs are rarely involved. We report the first case of ocular MMP (OMMP) in a diabetic patient treated with gliclazide, a second-generation oral hypoglycaemic agent, belonging [...]