John Libbey Eurotext

European Journal of Dermatology


Intravascular large NK/T-cell lymphoma: a variant of extranodal NK/T-cell lymphoma, nasal type? Volume 29, numéro 4, July-August 2019


  • Figure 1
1 Fourth Clinical College, Zhejiang University of Traditional Chinese Medicine, China
2 Department of Dermatology, the Affiliated 3rd Hospital of Hangzhou, Anhui Medical University, Hangzhou, 310009, China

A man in his 40s presented with a one-year history of nasal congestion. One year ago, the patient underwent PET-CT and imaging findings revealed soft tissue density in the left nasal cavity. Biopsy showed an infiltrate with a large number of atypical lymphocytes in the deep dermis. Angiocentric and angio-invasive infiltrates could be found. Immunohistochemistry for granzyme B, TIA-1, and CD56 and in situ hybridization for EBER were positive and negative results were obtained for CD30, D-240, CD31, [...]