John Libbey Eurotext

European Journal of Dermatology


Comparison of genetic mutations in squamous cell carcinoma and actinic keratosis of the forehead in the same patient using whole-genome sequencing Volume 31, numéro 4, July-August 2021


  • Figure 1
1 Department of Life Science, Dongguk University-Seoul, Ilsandong-gu, Goyang-si, Gyeonggi-do, Republic of Korea
2 Department of Dermatology, College of Medicine, The Catholic University of Korea

Actinic keratosis (AK) is a common skin disorder composed of proliferative and transformed keratinocytes. AK occurs in sun-exposed areas in middle-aged and older fair-skinned subjects and is related to chronic ultraviolet (UV) exposure [1, 2]. The age-adjusted incidence of AK in South Korea was 4.29 per 10,000 person-years in 2015 [3].AK has been considered a premalignant lesion with a potential to develop into squamous cell carcinoma (SCC), and early diagnosis and immediate treatment of AK have [...]