John Libbey Eurotext

European Journal of Dermatology


Comedones appearing after herpes zoster infection: Koebner phenomenon or Wolf's isotopic response? Volume 29, numéro 2, March-April 2019


  • Figure 1
Department of Dermatology, Radboud university medical center, Nijmegen, The Netherlands

Wolf proposed the term “isotopic response” to describe the appearance of a new, unrelated skin disease at the site of another healed skin disease [1]. We report a patient who developed comedones at the site of healed herpes zoster.A 34-year-old immunocompetent woman presented with asymptomatic black lesions at the right side of her back, confined to a single dermatome. The medical history revealed a herpes zoster infection at the same location five months before the eruption of the black lesions. [...]