John Libbey Eurotext

European Journal of Dermatology


CD8+, CD56+ erythrodermic mycosis fungoides with an indolent clinical behaviour Volume 29, numéro 3, May-June 2019


  • Figure 1
1 Department of Dermatology and Venereology,
2 Department of Pathology, Peking University First Hospital, Beijing, China

Classic mycosis fungoides (MF) presents a CD2+, CD3+, CD4+, CD8-, helper T-cell immunophenotype. Less than 5% MF cases have a cytotoxic T-cell phenotype (CD3+, CD4-, CD8+) associated with the expression of the cytotoxic proteins, T-cell intracellular antigen (TIA)-1 and granzyme B [1]. CD8+, CD56+ MFs are very rare. Erythrodermic MF, clinically classified as T4 stage, usually demonstrates very poor prognosis, with a five-year survival rate, ranging from 27% to 40% [2]. We herein report a case of [...]