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European Journal of Dermatology

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Anetoderma with lesional infiltration of TNF-alpha-expressing basophils and matrix metalloproteinase-9-secreting M2 macrophages Volume 31, numéro 2, March-April 2021

Illustrations


  • Figure 1
Auteurs
Department of Dermatology, National Defense Medical College, Tokorozawa, Japan

Anetoderma (also known as macular atrophy) is a rare elastolytic disease clinically characterized by small, atrophic or flaccid patches that herniate inward on palpation [1]. Histopathological examination reveals complete loss (elastolysis) and/or fragmentation (elastorrhexis) of elastic fibres in the upper and mid-dermis, occasionally accompanied by inflammatory infiltrates comprising lymphocytes, eosinophils, neutrophils, macrophages, and/or multi-nucleated giant cells [1, 2]. Furthermore, elastophagocytosis [...]