John Libbey Eurotext

European Journal of Dermatology

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A case of pemphigus with anti-desmoglein 3 and anti-desmocollin 2 and 3 autoantibodies, associated with follicular lymphoma and bronchiolitis obliterans Article à paraître

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Auteurs
1 Division of Dermatology, Japanese Red Cross Nagoya Daiichi Hospital, Nagoya, Japan
2 Department of Dermatology, Nagoya University Graduate School of Medicine, Nagoya, Japan
3 Department of Hematology and Gene Research Lab, Nagoya University Graduate School of Medicine, Nagoya, Japan
4 Department of Dermatology, Kurume University School of Medicine, Kurume, Japan
5 Department of Dermatology, Osaka City University Graduate School of Medicine, Osaka, Japan

Pemphigus is an autoimmune blistering disease involving both the skin and the mucous membranes in which autoantibodies against desmogleins (Dsgs), a group of desmosomal cadherins, cause intraepidermal acantholytic blisters. Desmocollins (Dscs) are another type of desmosomal cadherin, of which there are three isotypes: Dsc1-Dsc3 [1–3]. Here, we report a unique case of pemphigus with autoantibodies to desmoglein 3 and desmocollins 2 and 3, complicated with follicular lymphoma and bronchiolitis obliterans [...]