Annales de Gérontologie


The usefulness of FAB scale in the screening of mild cognitive impairment in elderly patients with newly diagnosed Parkinson’s disease Volume 2, numéro 2, avril 2009

Neurologue, Service de Gériatrie, Hôpital Bretonneau, Paris, Psychologue, Service de Gériatrie, Hôpital Bretonneau, Paris, Chef de Service de Gériatrie, Hôpital Bretonneau, Paris, Chef de Service de Psycho-Gériatrie, Hôpital Bretonneau, Paris

Early cognitive changes in patients with Parkinson’s disease (PD) are often subtle and influenced by factors that interact with the disease process such as the age-at-onset of disease. Executive function deficits are the most frequently reported cognitive disorders. The aim of this study was to determine the frequency and pattern of cognitive dysfunction in patients with newly diagnosed PD in function of the age-at-onset of disease and to assess the usefulness of the FAB scale. This prospective study included 56 consecutive patients with newly diagnosed PD. Patients have been classified according to age: ≥ 75 years (group 1, 33 patients), < 75 years (group 2, 23 patients) and compared with a control group ≥ 75 years (group 3, 30 patients) without extrapyramidal signs or cognitive impairment. MMS and FAB scores were lower in the first group than in the second one, while memory complaints were comparable in both groups. When compared with the control group, only FBI scores have shown a statistical difference between the groups 1 and 3. These findings must be considered in the management of PD in elderly subjects particularly in medications prescription and home care supports, and could provide an explanation for the higher risk of progression to dementia.