Sang Thrombose Vaisseaux
MENUPleiotropic effects of heparins, potential interest in SARS-CoV-2 infections Volume 34, issue 2, March-April 2022
Authors
1 CREATIF, Centre de référence et d’éducation aux antithrombotiques d’Ile de France, 2, rue Ambroise Paré, 75010 Paris, France
2 Hôpital Lariboisière, service de cardiologie, 2, rue Ambroise Paré, 75010 Paris, Paris
3 Hôpital Saint-Joseph, service de médecine vasculaire, 185, rue Raymond Losserand, 75014 Paris, France
* Tirés à part : L. Drouet
- Key words: heparin, Covid-19, SARS-CoV-2
- DOI : 10.1684/stv.2022.1195
- Page(s) : 89-97
- Published in: 2022
Heparins are made up of glycosaminoglycan chains that we do have known and used for decades for their anticoagulant properties mainly anti-Xa and anti-IIa. In recent years, apart from anticoagulant effects, attention was drawn to the pleiotropic effects of heparins. Some of these effects are potentially useful in the management of patients infected with Covid-19. Indeed in vitro studies reveal many potential side effects of heparins that could be useful in such viral infections, and clinical studies reinforce the interest and the effectiveness of heparin in patients infected with this virus.