JLE

Néphrologie & Thérapeutique

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Urinary mRNA analysis of biomarkers to epithelial mesenchymal transition of renal allograft Volume 14, issue 3, Mai 2018

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Authors

1 IntroductionChronic allograft nephropathy (CAN), characterized by progressive renal dysfunction accompanied by interstitial fibrosis and tubular atrophy (IFTA), vascular occlusive changes, and glomerulosclerosis, is an outcome common to various causes of renal allograft loss including acute rejection episodes, hypoperfusion, ischaemia-reperfusion, calcineurin toxicity, infection and recurrent disease. CAN is determined by a relatively slow but variable rate of decline in renal function after the [...]