John Libbey Eurotext

Médecine de la Reproduction

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Pregnancy bioengineering: getting rid of the uterus? Volume 24, issue 2, Avril-Mai-Juin 2022

Figures

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Authors
1 Université Paris-Saclay, UVSQ, Inrae, Breed, Jouy-en-Josas, France.
2 Médecine et réanimation néonatales, CHI Poissy St-Germain-en-Laye, Poissy, France <olivier.sandra@inrae.fr>
* Tirés à part : O. Sandra

The uterus is the specialised female organ that enables a pregnancy to result in a birth. In order to treat or circumvent uterine infertility, various therapeutic strategies are currently used. This review presents and discusses recent advances in the fields of in vitro development of peri-implantation embryo, biotechnological devices that mimic placental function and regenerative medicine applied to the uterus. To date, none of the available approaches allows the uterus to be bypassed in order to ensure the development of the embryo from implantation to term, outside the maternal body.