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Transcranial magnetic stimulation: Benefits and specific characteristics in the treatment of depression in the elderly Volume 98, issue 10, Décembre 2022

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Authors
# Ilia Humbert et Samuel Bulteau ont contribué de façon équivalente au travail de rédaction.
1 CNRS UMR 7357 ICube, Université de Strasbourg, France
2 Fédération de médecine translationnelle de Strasbourg (FMTS), Université de Strasbourg
3 Centre de neuromodulation non-invasive de Strasbourg (Cemnis, UF 4768), service de physiologie et d’explorations fonctionnelles, Hôpitaux universitaires de Strasbourg, 1 pl. de l’Hôpital, BP 426, Strasbourg
4 Section stimulation transcrânienne en psychiatrie (STEP) de l’Association française de psychiatrie, biologique et de neuropsychopharmacologie, Saint-Germain-en-Laye, France
5 Unité de recherche clinique, EPS Ville-Évrard, pôle G03, 202, avenue Jean-Jaures, 93330 Neuilly/Marne, France
6 CHU de Nantes, Service de Psychiatrie de liaison et d’addictologie, Nantes
7 Université de Nantes, Faculté des sciences du Sport, Laboratoire « Mouvement, Interactions, Performance » (EA 4334), Nantes
8 Université de Nantes, Université de Tours, Inserm, Sphere U1246, Nantes
9 Service de Psychiatrie, Centre Ressource de psychiatrie du sujet âgé, Hôpital Corentin-Celton, Université Paris Descartes 92130 Issy-les-Moulineaux, France
Correspondance : I. Humbert

Following the increasing awareness of the reality of mood disorders in the elderly, with all their specific characteristics, psychiatrists have been looking for the most suitable therapeutic responses. Among the innovative techniques at their disposal, repetitive transcranial magnetic stimulation (rTMS) seems to be a good option: Its effectiveness, which has been demonstrated in the treatment of depression in the general population, is particularly marked in the elderly. In addition, its excellent tolerance profile appears to be well suited to a geriatric population that is sensitive to adverse pharmacological effects. An ideal treatment for depression in the elderly? We will show that rTMS also has limitations in this context. For example, physiological or pathological aging processes, such as neurodegenerative diseases and strokes, impose constraints on the use of rTMS.