CHU Lille, Hôpital Claude-Huriez, Pôle médico-chirurgical, Service des maladies de l’appareil digestif, 59037 Lille Cedex
CHU Lille, Hôpital Claude-Huriez, Pôle médico-chirurgical, Service de chirurgie digestive et transplantation, 59037 Lille Cedex
Hepatocellular carcinoma develops in 20 to 30% of cases in non-cirrhotic liver, most often in Western countries on metabolic-related chronic liver disease. Hepatocellular carcinoma in non-cirrhotic liver constitutes a particular entity. It affects older subjects with a less marked male predominance, is discovered on clinical symptoms at a later stage than in cirrhosis, its diagnosis is histological and its standard curative treatment is surgical resection. Its late discovery constitutes a difficulty in the prognostic evaluation compared to hepatocellular carcinoma developed on cirrhosis.