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Hépato-Gastro & Oncologie Digestive

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Last up-date on French colorectal epidemiology Volume 15, special issue 6, Numéro spécial : Actualité 2008

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Authors
Registre Bourguignon des Cancers Digestifs (Inserm U866). Faculté de Médecine, 7 boulevard Jeanne d’Arc, BP 87900, 21079 Dijon Cedex, France

Descriptive epidemiologic data is needed to know incidence, trend in incidence over time, geographic repartition of illnesses and to identify risk groups. In 2005, 37,413 new colorectal cancers cases were diagnosed in France. For both sexes, colorectal ranked 3 rd among all cancers. Its incidence remained stable since 1980, in spite of a shift from left colon cancers to right colon cancers. Subjects with average risk are those for both sexes, aged more than 50 years. Colorectal mass screening, which has started in France since 2001, aims this population. Epidemiologic data suggest that patients with familial history of adenomatous larger than 1 cm are at high risk of colorectal cancer. These patients should have the same pattern of management than patients with family history of colorectal cancer. Three to five percent of colorectal cancers occur in the context of well known hereditary syndromes. In these families, the identification of a pejorative mutation has to be done to the index case and proposed to their first degree relatives, in order to set an adapted screening strategy.