Hépato-Gastro & Oncologie Digestive
MENUBacterial infections and cirrhosis except spontaneous bacterial peritonitis. 1st part : physiopathology and clinical specificities Volume 24, issue 3, Mars 2017
Authors
1 CHU Côte de Nacre,
service d’hépato-gastro-entérologie,
Avenue de la Côte de Nacre,
14033 Caen,
France
service d’hépato-gastro-entérologie,
Avenue de la Côte de Nacre,
14033 Caen,
France
* Tirés à part
- Key words: bacterial infections, cirrhosis, epidemiology, risks factors, treatment
- DOI : 10.1684/hpg.2017.1422
- Page(s) : 241-8
- Published in: 2017
Due to complex immune dysfonction, cirrhotic patients are prone to develop bacterial infections which lead to a 4-fold rise of mortality. Some risk factors are clearly identified such as chronic excessive alcohol intake, degree of liver failure and intestinal bleeding. Recently, new risks factors have been identified such as type 2 diabete, chronic use of proton pump inhibitors and positive viral load in case of chronic hepatitis C infection. Most common infections are spontaneous bacterial peritonitis, pneumonia, urinary tract infection, bacteremia and soft tissue infection. Resistant bacteria and fungal infections are increasing.