John Libbey Eurotext

Gériatrie et Psychologie Neuropsychiatrie du Vieillissement


Évaluation neuropsychologique des adultes porteurs d’une trisomie 21 en Consultation mémoire : quels outils ? Une revue de la littérature Volume 20, issue 1, Mars 2022



1 CMRR vieillissement du CHRU de Nancy, Service de gériatrie, CHRU de Nancy, Hôpitaux de Brabois, Vandœuvre-Lès-Nancy, France
2 CMRR, Service de neurologie, CHU Amiens; Laboratoire de Neurosciences Fonctionnelles Et Pathologies (LNFP) EA 4559
3 Université de Lorraine, Laboratoire APEMAC EA 4360
* Tirés à part : A. Coquelet

Improvement of life expectancy in people with Down syndrome (DS) is associated with new problems such as cognitive decline associated with aging and screening/diagnosis for Alzheimer's disease (AD) in this population. The aim of this review is to identify the main tools used in the literature for the cognitive evaluation in this population.Research was conducted on PsycINFO, PubMed, Web of Science and Wiley databases and Google Scholar from July to November 2020, concerning persons with DS, aged of 18 years or more, and evaluated with cognitive assessment scales.196 assessment tools were identified among the 85 articles included. However, most tools had not been validated in French, and only one third were specifically designed for a diagnosis of AD in people with DS. These results underline the need to develop specific tools for the diagnosis of AD in people with DS and validated in French.