John Libbey Eurotext

Environnement, Risques & Santé


Génotoxicité du dioxyde de titane : une revue des résultats publiés au cours des six dernières années Volume 20, issue 2, March-April 2021


This news is based on the following article: Carriere M, Arnal ME, Douki T. TiO2 genotoxicity: An update of the results published over the last six years. Mutat Res Gen Tox 2020 ; 854-855 : 503198. Doi : 10.1016/j.mrgentox.2020.503198.


This analysis of some 60 scientific articles on TiO2 genotoxicity published in the last 6 years suggests that this highly controversial topic remains of interest. The review shows that TiO2, as both nano- and micro-particles, damages the DNA of numerous cell and tissue types even at low doses corresponding to real exposure situations. It supports the possible 2B carcinogenic classification made by the World Health Organization's International Agency for Research on Cancer (IARC), and confirms the recent European classification of this molecule as possibly carcinogenic by inhalation.