John Libbey Eurotext

Environnement, Risques & Santé


Exposition aux phtalates et neurodéveloppement : revue systématique de la littérature et méta-analyse des données épidémiologiques humaines Volume 20, issue 2, March-April 2021


This news is based on the following article: Radke EG, Braun JM, Nachman RM, Cooper GS. Phthalate exposure and neurodevelopment: A systematic review and meta-analysis of human epidemiological evidence. Environ Int 2020 ; 137 : 105408. Doi : 10.1016/j.envint.2019.105408.

Phthalates are known as endocrine disruptors. Several studies suggest that fetal and early childhood exposure to phthalates is associated with neurodevelopmental disorders. This review of the epidemiological literature on the subject suggests that the association between exposure and children's neurodevelopment is either weak or impossible to demonstrate, with the exception of motor effects for butyl benzyl phthalate (in girls only), which are moderately significant.