Exploration of episodic memory by fonctional imaging: results by adults Volume 18, supplement 2, Numéro spécial, Septembre 2006


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Unité d’Épileptologie, 41 bd de l’Hôpital, 75013 Paris, France

Historically, the memory was presumed to be subserved by the Papez circuit. Functional imaging, either positron emission tomography or functional MRI, has helped to change this historical concepts. Recent findings have converged on the observation that hippocampal or parahippocampal regions could be consistently activated in verbal or visuospatial memory paradigms. Furthermore, these functional neuroimaging studies have also stressed the importance of the prefrontal and parietal cortical activations in such memory processes. These results show that memory is subserved by a more widely distributed cortical network than expected. The plasticity of these circuits must be now explored in epileptic patients.