John Libbey Eurotext

Two related cases of super-refractory status epilepticus due to 4-aminopyridine intoxication and an overview of the literature Volume 23, issue 3, June 2021


(1) What is the most likely cause when one is confronted with refractory status epilepticus in two persons living in the same house?


(2) What are the most important side effects of 4-Aminopyridine?


(3) How to treat a suspicion of intoxication when the causal agent is unknown?








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(1) Intoxication.


(2) Hypersalivation, sweating, tremor, epileptic convulsions and cardiac arrhythmia.


(3) Active charcoal administration within the hour.







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