Epileptic Disorders


The response to ACTH is determined early in the treatment of infantile spasms Volume 17, issue 1, March 2015

Figure 1

The response to ACTH by diagnostic aetiology.

Malformation: malformation of cortical development; HIE: hypoxic ischaemic encephalopathy; IVH: intraventricular haemorrhage; PVL: periventricular leukomalacia.

Figure 2

One-minus-survival plot illustrating the percent of seizure remission as a function of ACTH treatment days.

The dashed line represents the short course ACTH protocol (n=14); the solid line represents the long course ACTH protocol (n=25). Time to remission did not differ by protocol; p=0.26 (log-rank test).