JLE

Epileptic Disorders

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Rage and aggressive behaviour in frontal lobe epilepsy: description of a case and review of the mechanisms of aggressive behaviour in epilepsy and dementia Volume 23, issue 2, April 2021

Figure 1

(A-D) MRI scan showing a dysplasia on the dorsolateral prefrontal cortex: (A) fluid-attenuated inversion recovery image; (B) inversion recovery-weighted coronal image; (C) T2-weighted coronal image; (D) T2-weighted axial image. (E) Localization of the dysplastic lesion is shown in yellow after manual segmentation using volumetric T2-weighted scanning. The pial surfaces were generated using the Free-surfer pipeline. (F) Ictal EEG showing a right fronto-centro-temporal theta rhythmic discharge (yellow arrow). ECG channel shows a sinus tachycardia during the seizure. Muscle artifacts partially covered the onset of the seizure. Calibration = 100μV/cm; EMG2 = right deltoid muscle; EMG3 = left deltoid muscle; ECG = electrocardiogram. (G) Topographic EEG maps of spectral power for distinct frequency bands during the first 10 seconds of a seizure. Alpha, theta and beta activities show asymmetrical distribution on the frontal regions (referential montage absolute scale, LF 1.60 - HF 70Hz, AVG, FFT tapering and detrending, interpolazione spline pl). (H) Topographic EEG maps of spectral power for distinct frequency bands during 10 seconds of the eyes-closed resting state. The oscillations remain largely symmetrical (referential montage absolute scale, LF 1.60 - HF 70Hz, AVG, FFT tapering and detrending, interpolation spline pl). L: left.