John Libbey Eurotext

Lingual epilepsia partialis continua: a detailed video-EEG and neuroimaging study Volume 22, issue 4, August 2020


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1 Department of Clinical Neurophysiology, Marqués de Valdecilla University Hospital,
2 Department of Physiology and Pharmacology, University of Cantabria (UNICAN),
3 Biomedical Research Institute (IDIVAL),
4 Department of Radiology, Marqués de Valdecilla University Hospital,
5 Department of Neurology, Marqués de Valdecilla University Hospital,
6 Department of Intensive Medicine, Marqués de Valdecilla University Hospital, Santander, Cantabria, Spain
* Correspondence: José L. Fernández-Torre Department of Clinical Neurophysiology, “Marqués de Valdecilla” University Hospital, Avda. Valdecilla 25, 39008 Santander, Cantabria, Spain

Motor epilepsia partialis continua (EPC) is a frequent and widely described variant of simple focal motor status epilepticus. However, lingual EPC is an unusual epileptic condition. We present a case of lingual EPC secondary to low-grade glioma in which the EEG and neuroimaging features were particularly remarkable. The video-EEG showed lateralized periodic discharges with superimposed rhythmic activity and frequent recurrent focal epileptic seizures. Moreover, brain magnetic resonance imaging showed a right temporo-insular cortico-subcortical lesion which was hyperintense on FLAIR, suggestive of low-grade glioma. In addition, diffusion-weighted imaging and arterial spin labelling series showed restricted diffusion in the right temporo-insular and parietal cortex and increased cerebral flow, respectively. All these findings are in keeping with changes related to persistent focal status epilepticus. Finally, we review the literature and discuss the differential diagnosis of this rare epileptic entity. [Published with video sequence].