Epileptic Disorders
MENULate adult-onset epilepsy in a patient with hemimegalencephaly Volume 21, issue 2, April 2019
Authors
Departments of Clinical Neurological Sciences (SAC, SMM), Medical Imaging (SMM), Medical Biophysics (SMM), Psychology (SMM), Western University, London, Canada
* Correspondence: Seth Climans
Department of Clinical Neurological Sciences,
Room B7-005,
339 Windermere Road,
London, Ontario,
N6A 5A5, Canada
- Key words: focal epilepsy, malformations of cortical development, hemimegalencephaly
- DOI : 10.1684/epd.2019.1041
- Page(s) : 206-8
- Published in: 2019
Hemimegalencephaly is a malformation of cortical development that normally manifests in childhood with seizures and cognitive impairment. We present a case of hemimegalencephaly in a 55-year-old developmentally-normal woman who developed focal impaired awareness seizures with bilateral tonic-clonic spread. Her interictal EEG showed left-sided multifocal spikes, and ictal EEG showed seizures starting in the left hemisphere. Imaging showed hemimegalencephaly. This case may represent the oldest age for a first seizure in a patient with hemimegalencephaly.