John Libbey Eurotext

Epilepsy surgery for patients with genetic refractory epilepsy: a systematic review Volume 20, issue 2, April 2018


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1 Department of Child Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht
2 Department of Genetics, Center for Molecular Medicine, University Medical Center Utrecht, The Netherlands
* Correspondence: Kees PJ Braun University Medical Center Utrecht, PO Box 85090, Heidelberglaan 100 3508 Ab Utrecht, The Netherlands


In recent years, many different DNA mutations underlying the development of refractory epilepsy have been discovered. However, genetic diagnostics are still not routinely performed during presurgical evaluation and reports on epilepsy surgery outcome for patients with genetic refractory epilepsy are limited. We aimed to create an overview of the literature on seizure outcome following epilepsy surgery in patients with different genetic causes of refractory epilepsy.