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Epileptic Disorders

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Electrophysiological characterisation of myoclonic-atonic seizures in symptomatic continuous spike-waves during slow sleep syndrome Volume 11, issue 1, March 2009

Figure 1 Cerebral MRI showing a large sequellar lesion in the right middle cerebral artery territory, sparing the thalamus.

Figure 2 Sleep EEG before any treatment. Nearly continuous diffuse asymmetrical spike-waves, predominant on the right side (300 Î¼V, 1 sec).

Figure 3 Secondary generalized epileptic myoclonus, followed by brief silent period. The onset of the myoclonus is time-locked to the peak of the negative spike on the controlateral central electrode. “Premyoclonic” spike and myoclonus are clearly asynchronous.

Figure 4 Awake EEG, no treatment. Three massive myoclonic jerks were recorded on deltoid EMG, correlating with the negative spike component of a bilateral spike and wave complex predominant on the right centrotemporal region (500 ÂµV, 1 sec). The third spike-wave discharge is asymptomatic.