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Delayed seizure control with responsive neurostimulation: patience is a virtue Volume 18, issue 1, March 2016

Authors
1 Department of Neurosurgery,
2 Department of Neurology at Mayo Clinic, Jacksonville, 4500 San Pablo Road, Jacksonville, Florida 32224, USA

To the Editor,The efficacy of neurostimulation using vagus nerve stimulation (VNS), deep brain stimulation of the anterior nucleus of the thalamus, and responsive neurostimulation (RNS) has been shown to improve over time (Heck et al., 2014). RNS was recently approved by the United States Food and Drug Administration (USFDA) based on controlled trials that demonstrated safety and efficacy despite a third of patients failing epilepsy surgery and VNS (Heck et al., 2014). The USFDA approval employed [...]