John Libbey Eurotext

De novo late-onset absence status epilepticus or late-onset idiopathic generalized epilepsy? A case report and systematic review of the literature Volume 20, issue 2, April 2018

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Authors
1 Department of Neurosciences, Biomedicine, and Movement Sciences, University of Verona
2 Division of Neurology, Franz Tappeiner Hospital, Merano, Italy
3 Department of Neurology, Christian Doppler Medical Centre, Paracelsus Medical University, Salzburg
4 Center for Cognitive Neuroscience, Salzburg
5 University for Health Sciences, Medical Informatics and Technology, Hall IT, Austria
* Correspondence: Francesco Brigo Department of Neurosciences, Biomedicine, and Movement Sciences, University of Verona, Piazzale L.A. Scuro, 10 - 37134 Verona, Italy

Aim

Idiopathic (genetic) generalized epilepsies (IGEs) are age-related epileptic syndromes with typical age onset in childhood or adolescence. We report a patient with de novo late-onset absence status epilepticus (ASE) occurring at the age of 64 years, with clinical and EEG features suggestive of late-onset IGE. We also discuss the relationship between de novo late-onset ASE and late-onset IGE, and provide a comprehensive and critical review of the available literature on late-onset (i.e. onset ≥60 years) IGE.