Epileptic Disorders
MENUCardioembolic acute cerebral micro-infarcts in the context of atrial fibrillation after low-dose intravenous infusion of lacosamide Volume 22, issue 1, February 2020
Authors
Aims
Department of Neurology, Hospital Universitario Ramón y Cajal. Madrid, Spain
* Correspondence: Álvaro Beltrán Corbellini
Secretaría de Neurología,
Hospital Universitario Ramón y Cajal, Crta,
Colmenar, Km 9, N° 100. Madrid, Spain
- Key words: status epilepticus, lacosamide, arrhythmia, atrial fibrillation, stroke, elderly
- DOI : 10.1684/epd.2020.1136
- Page(s) : 83-9
- Published in: 2020
Lacosamide (LCM) is a well-tolerated and increasingly used second-generation AED, and side effects such as atrial fibrillation are rare and poorly characterized. Supported by a literature review, we share our experience of the management of the first reported case of cardioembolic cerebral infarcts in the context of de novo atrial fibrillation, which appeared following a 200-mg intravenous infusion of LCM for the treatment of non-convulsive status epilepticus.