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European Journal of Dermatology

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Valacyclovir-induced drug reaction with eosinophilia and systemic symptoms Volume 32, issue 4, 2022-07-01

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Authors
Department of Dermatology, Faculty of Medicine, Academic Assembly, University of Toyama

Drug reaction with eosinophilia and systemic symptoms (DRESS) is a severe adverse drug reaction with multiorgan system and cutaneous involvement. Although the exact pathogenesis is unclear, a complex interplay of various drugs, human herpesvirus reactivation and immune abnormalities has been suggested [1]. We herein report a case of DRESS caused by valacyclovir.A 101-year-old woman was referred for the evaluation of a cutaneous rash, facial oedema, cough and fever. She had been treated with olmesartan [...]