John Libbey Eurotext

European Journal of Dermatology

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A case of multiple juvenile xanthogranuloma with unusual clinicopathological features Volume 32, issue 5, September-October 2022

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Authors
1 Department of Dermatology, Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China
2 Department of Pathology, Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China
a These authors contributed equally

Juvenile xanthogranuloma (JXG) is a benign xanthogranulomatous disease that is mainly characterized by yellow, red, or brown nodular skin lesions. It is a non-Langerhans histiocytic benign proliferative disease and often occurs in infancy or early childhood [1]. The significant histopathological features of the disease are Touton multinucleated giant cells, and positivity for CD68 but not CD1a or S100 protein on immunohistochemistry [2]. Multiple JXG is unusual in Asians, and nail involvement of [...]