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Dendritic cells (DC) promote natural killer (NK) cell functions: dynamics of the human DC/NK cell cross talk Volume 13, numéro 1, March 2002

Auteurs
Unité d'Immunologie, Département de Biologie Clinique, Institut Gustave-Roussy, 39, rue Camille-Desmoulins, 94805 Villejuif Cedex, France.
  • Page(s) : 17-27
  • Année de parution : 2002

INTRODUCTION NK cells are a subpopulation of lymphoid cells that were originally defined by their ability to lyse infected or transformed target cells without prior immunization. They represent one of the major effector cells of the non-antigen specific innate immunity. The mechanisms involved in target cell recognition and lysis by activated NK cells have been extensively studied, particularly with regard to the role of MHC class I-specific [...]