John Libbey Eurotext

Magnesium Research

Analysis of the effect of perioperative magnesium sulphate on minimal alveolar concentration of desflurane using bispectral index monitoring Volume 24, issue 4, December 2011

  • Auteur(s) : Yakup Tomak, Murat Tekin, Ismail Kati, Ceyda Belenli, Meltem Aydogmus , Department of Anesthesiology, Faculty of Medicine, Rize University, Rize, Turkey, Department of Anesthesiology, Faculty of Medicine, Kocaeli University, Kocaeli, Turkey, Department of Anesthesiology, Faculty of Medicine, Yuzuncu Yil University, Van, Turkey
  • Mots-clés : magnesium, desflurane, minimal alveolar consantration, bispectral index
  • Page(s) : 181-8
  • DOI : 10.1684/mrh.2011.0294
  • Année de parution : 2012

<p>In this study we aimed to analyze the effect of perioperative magnesium sulphate (MgSO 4) on minimal alveolar concentration (MAC) of desflurane using bispectral index (BIS) monitoring.</p><p>Sixty patients undergoing abdominal surgery under general anesthesia were randomized into two groups: Mg – receiving perioperative MgSO 4 supplementation and C – control. Anesthesia was titrated to maintain the BIS value between 45-55.</p><p>MAC values, tachycardia and hypertension during intubation was found to be lower in group Mg compared to group C (p<0.001). Time to extubation, verbal cooperation and eye opening was longer in patients receiving infusion of MgSO 4 (p<0.001).</p><p>We concluded that perioperative MgSO 4 infusion may be used as an adjunct as it decreases MAC of desflurane and suppresses the hemodynamic response to intubation.</p>