Auteur(s) : J.P.A. van Pelt, E.M.G.J. De Jong, P.E.J. van Erp, P.C.M. van de Kerkhof, cutaneous adverse drug reaction, hypersensitivity, betalactam antibiotics, urticaria, maculo-papular rash, erythema multiforme, fixed drug eruption..
Illustrations
Figure 1. Right angle scatter (RAS) versus forward scatter (FS) of a
leukocyte suspension. Several distinct cell populations can be recognised:
(a) unlysed erythrocytes and debris; (b) lymphocytes; (c) monocytes; (d)
PMN. This population of PMN is gated out to assess the FITC-fluorescense
of every cell which correlates with the number of CD11b molecules present
on the cell surface.
Figure 2. CD11b surface-expression (mean fluorescence units per cell)
of PMN in psoriatic patients and healthy volunteers.
Figure 3. Correlation between the number of CD11b molecules present on
unstimulated peripheral blood PMN and the increased number that is present
on these PMN after in vitro stimulation with LTB4.