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Super-refractory status epilepticus in autoimmune encephalitis treated with interleukin-1 receptor antagonist, anakinra Volume 23, numéro 3, June 2021

Figure 1

Treatment timeline up to discharge from the intensive care unit.

IVIg: intravenous immunoglobulin; IVMP: intravenous methylprednisolone; PLEX: plasma exchange.

Figure 2

(A) Coronal FLAIR MRI on Day 38 of presentation demonstrating increased T2/FLAIR signal intensity over bilateral mesial temporal regions. (B) Coronal FLAIR MRI on Day 80 of presentation demonstrating resolution of the increased T2/FLAIR signal intensity and development of bilateral mesial temporal sclerosis/atrophy.

Figure 3

(A-E) EEGs upon an attempt to wean the patient off general anaesthetic agents, demonstrating evolution of 3-3.5-Hz spikes from a burst suppression background. (F) EEG after completion of anakinra, demonstrating a more organised background without interictal discharges.