JLE

Epileptic Disorders

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Selection criteria and preoperative investigation of patients with focal epilepsy who lack a localized structural lesion Volume 2, numéro 4, Décembre 2000

Auteurs
Department of Neurology, Miami Children's Hospital, 3200 SW 60th Court, Miami, Florida 33155, USA.
  • Page(s) : 219-26
  • Année de parution : 2001

Disorders causing INLE Cerebral microdysgenesis Histopathologic anomalies of neocortical architecture are frequently observed in patients with chronic epilepsy. Meencke and Janz [1, 2] noted minor histological changes ("microdysgenesis" ) in the frontal cortex of patients with primary generalized epilepsy, including increased ectopic neurons in white matter. While similar abnormalities appear in the molecular layer of normal brains [...]