John Libbey Eurotext

Epileptic Disorders

The Educational Journal of the International League Against Epilepsy

Resection of focal cortical dysplasia located in the upper pre-central gyrus Volume 17, numéro 4, December 2015

Illustrations

  • Figure 1
  • Figure 2
Auteurs
1 Department of Neurosurgery,
2 Department of Behavioral Neurology and Cognitive Neuroscience,
3 Department of Epileptology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan
* Correspondence: Masaki Iwasaki Department of Neurosurgery, Tohoku University Graduate School of Medicine, Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8574, Japan
  • Mots-clés : focal cortical dysplasia, epilepsy surgery, multimodal imaging, primary motor cortex, seizure outcome
  • DOI : 10.1684/epd.2015.0771
  • Page(s) : 479-84
  • Année de parution : 2015

The primary motor cortex of the oro-facial level can be removed without permanent deficits, because of the bilateral representation of the innate functions. In contrast, resective surgery of the hand motor cortex or higher levels presents more challenges. We treated two adult patients with intractable epilepsy caused by small focal cortical dysplasia in the pre-central gyrus located between the foot and hand primary motor cortices. Focal cortical resection was guided by cortical EEG and intra-operative motor evoked potential, resulting in seizure freedom without neurological deficits in both cases. These cases illustrate that resective surgery can be safely performed in the primary motor cortex even dorsal to the oro-facial level, as long as the critical regions of the hand and foot motor cortices remain intact. Accurate delineation of the anatomical lesion and functional areas using intra-operative neurophysiological monitoring is crucial for successful outcome of the surgery.