John Libbey Eurotext

Prospective study on concentration-efficacy and concentration-toxicity: correlations with lamotrigine serum levels Volume 4, numéro 1, March 2002

Auteurs
Department of Neurology and Epileptology, Weissenau (Epilepsiezentrum Bodensee), Weingartshofer Straße 2, D-88214 Ravensburg, Germany.
  • Page(s) : 49-56
  • Année de parution : 2002

The relationship between lamotrigine (LTG) serum concentration and clinical response in patients with epilepsy is controversial. Although the existence of a positive correlation between LTG serum concentration and clinical efficacy (reduction in seizure frequency) is supported by many studies [2-11], numerous other investigators, found non such correlation [12-20]. The findings regarding the correlation between LTG serum levels and adverse [...]