JLE

Epileptic Disorders

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Lesion-negative anterior cingulate epilepsy (WITH VIDEO) Volume 17, numéro 2, June 2015

Figure 1

Interictal scalp electrode recordings of generalized spikes, maximum in the central regions (Cz>Fz), and invasive electrode recording of bilateral mesio-frontal spikes, maximum in the left anterior cingulate region (le2/le3 and lf1/lf2).

Figure 2

Second-stage bilateral EEG implantation with six orthogonally placed electrodes in the right (A) and left frontal lobe (B).

Figure 3

(A) A 250-Hz high-frequency oscillation pattern was seen over-riding the sharp-wave population arising only from the RB1/RB2 electrodes in the right anterior cingulate region, in the inferior bank of the cingulate sulcus, anterior to the genu of the corpus callosum. (B) An evolving ictal onset high-frequency discharge is seen in the same electrode contacts RB1/RB2. (High-frequency filtre: 600 Hz; time constant: 0.0001 ms).

Figure 4

Post-operative MRI shows right medial frontal resection in saggital T1 (A) and axial T2-weighted (C) images. Second-stage bilateral EEG implantation with six orthogonally placed electrodes in right frontal lobe (B).

Figure 5

NeuN immunohistochemistry demonstrating several heterotopic neurons in deep white matter (200x) (A), normal neurons with disoriented dendrites (200x) (B), and hypertrophic neurons in the cortex, outside layer 5 (100x) (C).