Figure 2
Clinical course of epilepsy with myoclonic atonic seizures and chronic cerebellitis. Asterisks show the titres of antibodies that exceeded +3SD from the mean. Myoclonic atonic seizures resolved concurrently with a decrease in serum anti-GluN2B-CT and anti-GluD2-NT antibodies, and in CSF, anti-GluN2B-NT2 and anti-GluD2-CT, following ACTH therapy.
ACTH: adrenocorticotrophic hormone; CZP: clonazepam; GluR: glutamate receptor; GTCS: generalized tonic-clonic seizures; IVIG: intravenous immunoglobulin; LTG: lamotrigine; LEV: levetiracetam; m: month; mPSL: methylprednisolone; NMDA-type: N-methyl-D-aspartate-type; VPA: valproate; y: year; ZNS: zonisamide.