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Epilepsy with myoclonic atonic seizures and chronic cerebellar symptoms associated with antibodies against glutamate receptors N2B and D2 in serum and cerebrospinal fluid Volume 19, numéro 1, March 2017

Figure 1

Ictal EEG of myoclonic atonic seizures exhibited generalized spike and wave complexes.

Figure 2

Clinical course of epilepsy with myoclonic atonic seizures and chronic cerebellitis. Asterisks show the titres of antibodies that exceeded +3SD from the mean. Myoclonic atonic seizures resolved concurrently with a decrease in serum anti-GluN2B-CT and anti-GluD2-NT antibodies, and in CSF, anti-GluN2B-NT2 and anti-GluD2-CT, following ACTH therapy.

ACTH: adrenocorticotrophic hormone; CZP: clonazepam; GluR: glutamate receptor; GTCS: generalized tonic-clonic seizures; IVIG: intravenous immunoglobulin; LTG: lamotrigine; LEV: levetiracetam; m: month; mPSL: methylprednisolone; NMDA-type: N-methyl-D-aspartate-type; VPA: valproate; y: year; ZNS: zonisamide.