Epileptic Disorders
MENUCan diffusion-weighted imaging be used as a tool to predict seizures in patients with PLEDS? Volume 18, numéro 4, December 2016
TEST YOURSELF
(1) What is the exact clinical significance of finding PLEDs on the EEG of patients?
(2) Can diffusion restriction patterns be seen on brain MRI of patients with seizures?
Answers
(1) The exact clinical significance of finding PLEDs on the EEG is not entirely clear, although they have been associated with seizures and increased metabolism. It is not clear which of the patients are likely to have seizures and need to be treated aggressively with anti-seizure medications.
(2) Diffusion restriction patterns on MRI of patients in the peri-ictal state and during seizures and status epilepticus have been reported. These are somewhat reversible changes. It has been suggested that the ADC changes in epilepsy are related to cell damage caused by seizure.