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Adult-onset Rasmussen encephalitis associated with focal cortical dysplasia Volume 19, numéro 4, December 2017

Figure 1

EEG showing left fronto-centro-parietal epileptic activity.

Figure 2

(A) Initial MRI showing hyperintense FLAIR lesions of the left frontal superior gyrus. (B) Second MRI showing progression of the lesions. (C) MRI showing left sylvian valley atrophy.

Figure 3

(A) Significant architectural disorganization (cortical dysplasia), loss of neurons, and glial and neo-vascular reaction (probable cicatricial Rasmussen disease) in the cortex. (B) White matter with inflammatory, glial, and macrophagic reactions. (C) NeuN staining confirms architectural disorganization and loss of neurons in the cortex. (D) Immunostaining for CD3 shows a T-cell inflammatory reaction in the white matter (peri-vascular and parenchyma).