European Journal of Dermatology
MENUVitamin B12 allergy manifesting as lymphomatoid contact dermatitis Volume 30, numéro 3, May-June 2020
Illustrations
1 Department of Dermatology,
2 Department of Pathology, Sapporo City General Hospital,
3 Department of Shibaki Dermatology Clinic, Sapporo, Japan
- DOI : 10.1684/ejd.2020.3786
- Page(s) : 304-5
- Année de parution : 2020
Methylcobalamin, a form of vitamin B12, is widely used to treat vitamin B12 deficiency, peripheral neuropathy and diabetic neuropathy. Since it contains cobalt in the centre of a corrin ring, those with cobalt allergies may experience allergic skin eruptions from methylcobalamin intake. Here, we report a case of systemic contact dermatitis arising from the cobalt in methylcobalamin, characterized by palmoplantar eczema with histopathological T-cell lymphomatoid reaction.A 59-year-old Japanese female [...]