European Journal of Dermatology
MENUThe safety of calcitriol 3 mg/g ointment. Evaluation of cutaneous contact sensitization, cumulative irritancy, photoallergic contact sensitization and phototoxicity Volume 11, numéro 3, May - June 2001
Illustrations
Galderma R&D, 635, route des Lucioles, BP 87, 06902 Sophia Antipolis Cedex, France.
- Page(s) : 219-24
- Année de parution : 2001
It is well established that the skin plays an important role in vitamin D metabolism, and that 1alpha, 25-dihydroxyvitamin D3, (1,25-(OH),D3 or calcitriol) the endogenously produced, hormonally active form of vitamin D3, is essential for the maintenance of calcium homeostasis. In addition, studies have shown that epidermal keratinocytes and dermal fibroblasts, in addition to other body tissues and various tumor cells, have a specific receptor for [...]