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European Journal of Dermatology

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The hair follicle as a target for gene therapy Volume 11, numéro 4, July - August 2001

Auteurs
Department of Dermatology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.
  • Page(s) : 353-6
  • Année de parution : 2001

The hair follicle plays a pivotal role in cutaneous biology. As an epidermal appendage, it possesses a full complement of epidermal cell types, including keratinocytes, melanocytes, and Langerhans cells, which all reside in the follicle outer root sheath that is contiguous with the epidermis. When these cell types are lost from the epidermis (for example, through wounding, ultraviolet light, thermal or chemical injury), precursor cells [...]