John Libbey Eurotext

European Journal of Dermatology

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Surfactants have multi-fold effects on skin barrier functionSurfactants have multi-fold effects on skin barrier function Volume 25, numéro 5, September-October 2015

Illustrations

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Tableaux

Auteurs
1 Université de Lyon F-69008,
Lyon, France;
Laboratoire de Dermopharmacie et Cosmétologie, Laboratoire d’Automatique et de Génie des Procédés (LAGEP), UMR CNRS 5007,
Faculté de Pharmacie,
8, avenue Rockefeller,
69373 Lyon cedex 08, France
2 Johnson & Johnson Santé Beauté France,
Campus de Maigremont,
27100 Val de Reuil, France
3 Université de Lyon,
Université Lyon 1,
CPE Lyon, CNRS UMR 5265,
Laboratoire de Chimie Catalyse Polymères et Procédés (C2P2),
F-69616, Villeurbanne (France)
* Reprints
  • Mots-clés : contact angle, infrared spectroscopy, lipid extraction, skin barrier function, surfactants
  • DOI : 10.1684/ejd.2015.2587
  • Page(s) : 424-35
  • Année de parution : 2015

Graphical abstractSurfactants, due to their surface activity, are widely used in topical products to stabilize dispersions such as emulsions or microemulsions but also for their detergent properties in cleansing products and finally as enhancers to promote drug absorption in the skin [1, 2]. Frequent exposure of skin to surfactants may damage the stratum corneum (SC) barrier and can induce skin dryness and inflammation. The stratum corneum is made of corneocytes imbedded in a continuous lipid matrix. [...]