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European Journal of Dermatology

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Serum cytokine profiling in patients with actinic prurigo Volume 28, numéro 6, November-December 2018

Auteurs
1 Department of Dermatology,
General Hospital “Dr. Manuel Gea González”,
Mexico City,
Mexico
2 Department of Stomatology,
Institute of Biomedical Sciences,
Autonomous University of Ciudad Juárez,
Ciudad Juárez,
Chihuahua,
Mexico
3 Department of Immnunology,
National Institute of Cardiology “Dr. Ignacio Chávez”,
Mexico City,
Mexico

Actinic prurigo (AP) is a chronic inflammatory photodermatosis that affects the skin, mainly in photoexposed areas, the lips, and conjunctival mucosa. It is an abnormal response to sunlight [1, 2].The pathogenesis of AP is believed to be based on a hypersensitivity reaction due to the presence of CD4+ lymphocytes, eosinophils, and mastocytes, as well as the production of TNF-α, IL-2, and IgE [3]. In accordance with the Gell and Coombs classification [4], the physiopathology of AP could correspond [...]